Two people found dead, while 24 others have been hospitalised after the shooting at the Mandalay Bay hotel and resort on the Las Vegas Strip.  Danita Cohen,  University Medical Center spokeswoman said the hospital is still evaluating the condition of "many patients" with gunshot wounds in the wake of the shooting, but at least 14 were in critical condition.

Danita Cohen,  University Medical Center spokeswoman said the hospital is still accessing the condition of many patients who have gunshot wounds after the shooting, and that a minimum of 14  of these victims are in a critical condition.  

During a Route 91 Harvest country music festival performance, a firing of a weapon was heard, and the shot's appeared to be coming from an upper floor of the hotel.

News first broke out on Twitter, where concertgoers and other guests at the hotel, took to Twitter to tell the world what was going on.

It is currently unclear whether the violence has been caused by multiple shooters or a single gunman.Dozens were seen on aerial footage fleeing the Mandalay Bay, which was on lockdown. SWAT teams in armoured cars were seen driving up to the hotel.

Eyewitness Bryan Heifner spoke to CNN from a room in a hotel across from the Mandalay Bay, which he said he could see from his window.

"Mostly I heard the shots, just so many shots -- I just thought it was a semi braking with the air brakes, but then I went downstairs and saw people running and looking for family," he said.

"I immediately went back to my room, locked the door, turned the lights off."

Las Vegas Boulevard has been shut down, until further investigation.

University Medical Center spokeswoman Danita Cohen told the Associated Press that the hospital is taking in "several" people with gunshot wounds.